cyclosporin a — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0945	Cyclosporin A	Cyclosporine A,Ciclosporin,Cyclosporine	Phosphatase , Antibiotic , Complement System
	Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM).		Phosphatase , Antibiotic , Complement System
TP1845	Cyclosporin A-Derivative 1
	Cyclosporin A-Derivative 1 is a crystalline intermediate derived from the opening of cyclosporin A.
TP1387	Cyclosporin A-Derivative 2
	Derivative 2 is A novel Derivative of Cyclosporin A.Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin.
TP1405	Cyclosporin A-Derivative 1 Free base
	Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A.
T76220	Cyclosporin A-Derivative 3
	Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition [1] .
T19848	Cyclosporin B	7-L-Alanine-cyclosporin A,Antibiotic S 7481F2
	Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B i...
T34999	UNIL-088	UNIL 088
	UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapid...
T64488	6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A
	6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A is a useful organic compound for research related to life sciences and the catalog number is T64488.
T19971	Cyclosporin C	CsC,Cs-C,Cyclosporin-C	Antiviral , Antifungal
	Cyclosporin C (Cs-C) is a fungal metabolite against filamentous phytopathogenic fungi. Cyclosporin C has antifungal, antiviral, and immunosuppressant properties.		Antiviral , Antifungal
T21493	Cyclosporin H		Others
	Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosp...		Others
TN4761	Phellamurin		P-gp
	Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadmini...		P-gp
T31467	Dihydrocyclosporin A	Dihydrocyclosporin-A	Others
	Dihydrocyclosporin A (Dihydrocyclosporin-A) is closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A significantly inhibits promastigotes and intracellular amastigotes.		Others
TP1665	Cyclosporin D
	Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.
T19785	Isocyclosporin A	IsocyclosporinA,Isocyclosporin-A
	Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.
T25281	Cyclopeptolide 1	SDZ 90-215,Cyclopeptolide-1
	Cyclopeptolide 1 is a novel antifungal cyclopeptolide. Cyclopeptolide 1 is similar to cyclosporin A that consists of nine S-amino acids and R-lactic acid.
T82636	Cyclosporin U
	Cyclosporin U (SMP0V32C6L) is a cytostatic agent critical for the prevention of organ transplant rejection [1].
TN4749	Pepluanin A		P-gp
	Pepluanin A, shows a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport.		P-gp
T68594	NFAT:AP-1 inhibitor-10
	NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosp...
T82222	H-D-MeAla-EtVaI-VaI-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVaI-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
	H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe is a derivative of cyclosporin A lacking immunosuppressive properties with potential application in congenital muscular dystrophy resear...
T26090	Rioprostil	TR 4698,TR4698,Rioprostilum,TR-4698
	Rioprostil is a methyl prostaglandin E1 analog that decreases gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the treatment of gastric ulcers and gives significant protection...